Matchstick Technologies

Our MISSION is to develop easy-to-use and robust technologies for spawning tomorrow’s medical breakthroughs.

Matchstick Technologies, Inc. develops instruments and tools for the life sciences.  The Matchstick team includes experts in high power ultrasound and cavitation, as well as chromatin researchers who developed the original Fast-ChIP and MATRIX-ChiP high-throughput systems.

Our platform technology, PIXUL®, is a high-throughput sample preparation instrument that shears DNA and chromatin samples with industry-leading sample consistency and repeatability.

Introducing PIXUL®

PIXUL® Multi-Sample Sonicator Highlights:

  • Process 1-96 samples in parallel to avoid sample shearing bottlenecks in NGS applications
  • Up to 12 unique sonication conditions can be run on a single 96-well plate, allowing simultaneous processing of multiple sample types and rapid optimization of conditions for difficult samples
  • Compatible with chromatin, DNA, RNA, and protein from purified samples, cells, or tissues
  • Inexpensive consumables keep sample processing costs low
  • A short 15-minute coupling fluid circulation avoids lengthy water degassing processes

Matchstick’s premier product, PIXUL® (stands for PIXelated ULtrasound), is a tool that processes each and every well of a 96-well microplate consistently and quickly. PIXUL® was designed completely from the ground up to provide the end user with an easy to use tool that is simple to set up, simple to use, and generates consistent results day in and day out. No other sample preparation platform out there can match the power and convenience of PIXUL®.

PIXUL® is an ultrasound-based sample preparation platform that fragments DNA and chromatin into tight but random distributions. Ultrasound is propagated into the well where microbubbles are formed. The intense collapse of these microbubbles lead to high shear stresses that fragment the samples into desired size ranges.

PIXUL® was conceived by an epigenetics researcher, and designed and built by ultrasound engineers to take the guesswork out of sample preparation. With PIXUL™, sample preparation is no longer an “art form”, but instead a simple device that gives repeatable results day in and day out.

Introducing PIXUL®

For Genomic and Epigenetic solutions
see the Active Motif website

For Proteomics solutions – our new PIXUL-Pro®
is coming soon!

PIXUL® Testimonials